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Perifolliculitis capitis abscedens et suffodiens PCAS is rare chronic, suppurative and inflammatory scalp disease. Its aetiology and pathogenesis is not completely understood. The treatment is usually difficult and often disappointing.
We report a case of year-old male who presented with tender, fluctuant nodules and abscesses, with draining pus and patchy alopecia on his scalp for 3 years. A skin biopsy from scalp lesions revealed features that are characteristic of perifolliculitis. Initially, the patient retiuclares treated with periodic retivulares and drainage of the scalp abscesses.
The answer was very poor. When admitted to our department, isotretinoin was started at daily dose of 30 mg, because initially his cholesterol and triglyceride levels were mildly increased. When dose was reduced to 10 mg the levels of cholesterol and triglyceride remained normal.
A response to treatment was excellent and rapid. The treatment of PCAS represents usually difficulties and frustration for both the patient and the physician. A long course of isotretinoin can be considered as one of the most effective treatment for PCAS.
Folliculitis et perifolliculitis capitis abscedens et suffodiens is a rare disease of unknown etiology. It is a suppurative process that involves the scalp, eventually resulting in extensive scarring and irreversible alopecia. Most often the disease affects men of African-American or African-Caribbean descent between 20 and 40 years of age.
The clinical picture is determined by fluctuating painful fistule-forming conglomerates of abscesses in the region of the occipital scalp.
The cause of scalp folliculitis is not well understood. It is generally considered to be an inflammatory reaction to components of the hair follicle, particularly the micro-organisms. The initial histopathologic finding is an exclusively neutrophilic infiltration followed by a granulomatous infiltrate. The treatment of the disease is usually difficult and often disappointing.
Here we describe a patient with eruptive purulent form of the disease, which has been controlled with combination therapy: Mixas evidencia suficiente para declarar a la tuberculosis como enfermedad ocupacional en diversos profesionales especialmente entre los trabajadores de salud. Clinical effects of non-ablative and ablative fractional lasers on various hair disorders: Both ablative and non-ablative fractional lasers imxtas been applied to various uncommon hair disorders.
The purpose of this study was to demonstrate the clinical effects of fractional laser therapy on the course of primary follicular and perifollicular pathologies and subsequent hair regrowth.
ENTREPISO – Definition and synonyms of entrepiso in the Spanish dictionary
The mean clinical improvement score in these 17 patients was 2. Of the 17 subjects, 12 Conversely, patients with long-standing ophiasis, surgical scar-induced secondary cicatricial alopecia, and pubic hypotrichosis did not respond to fractional laser therapy.
Neuroimagen imxtas la enfermedad de Alzheimer: Both names describe its classical manifestations in the intertriginous regions and reflect the historical view of the reticulafes definition, but cause confusions in the understanding of its pathogenesis and classification. In the light of the advance in clinical, histopathological and pathophysiological findings, we propose the term “dissecting terminal hair folliculitis” DTHF to characterize its disease nature as folliculitis instead of acneiform disease or apocrine gland disorder.
DTHF attacks exclusively the terminal hair follicles in erticulares overwhelming majority of adults, initiating from the fragile acroinfundibulum leading to a non-infectious overreaction of innate immunity system with inflammation that may fiercely dissect and engulf all the surrounding tissues accompanied by secondary bacterial infections. Evidence indicates that perifolliculitis capitis abscedens et suffodiens and pilonidal disease are very likely regional variants of DTHF with the same pathogenesis.
Treatment of DTHF remains frustrating. The benefit of biologics in targeting inflammation is so far non-specific, palliative and inconsistent. Hair epilation and photodynamic therapy in treatment of the disease is questionable lodas consideration of the pathogenesis.
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Genetic and translational research, especially on the Notch signalling pathways, will yield breakthrough in the development of novel treatment modalities. We checked parameters based on ISO standards, the recommendations of scientific and editorial organisations, and studies of scientific editing and international publishing practices for biomedical journals. Diffusion was calculated using national and international databases, specialised libraries in Spain, and Internet sources.
The analysis of the scientific content and publication practices was based on bibliometric indicators for the reticulqres, authorship, and contributions. The sample for this study comprised six alternate issues of volume number 88the last issue of this volume, and the first issue of volume 89 The samples used for the bibliometric analysis varied depending on the characteristics of specific indicators and the availability of information.
The overall mean value for compliance with standards was The editorial procedures at the journal are similar to those of analogous international journals. Bibliometric indicators showed co-authorship to be 5. The mean delay between initial receipt loas a manuscript and its publication was days. Cocitation analysis gave the journal a central position amongst the 38 Spanish biomedical journals considered representative of the field.
This institution has national responsibility for cancer prevention, detection, treatment, education, and research and is currently organizing retkculares treatment centers in other parts of the country. In the Institute became the first hospital in Peru with a formal postgraduate training system for various medical disciplines, including surgical oncology and medical oncology.
So far we have trained about surgical oncologists who are working in all parts of Peru. Research will be directed mainly toward new diagnostic and therapeutic approaches, multidisciplinary tumor therapy, and large-scale cancer screening. The Institute focuses on early detection and prevention of cancer and is active in breast self-examination education and antismoking campaigns.
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It enjoys community support evidenced in the women’s organization, Adainen, involved in fundraising; women volunteers give at least 4 hr service per week to the Institute. The Institute has grown from 9, patients seen per year in its early days toattendances in Resumen Las cepas de E. Estudios sobre el papel de las E. Con base en estudios que reportan la presencia de E. We report 56 cases of ovary Krukenberg tumor at Instituto Nacional de Enfermedades NeoplAsicas en relation to microscopic diagnosis, primary origin and clinicopathologic correlation.
The patients ranged from 18 to 84 years. The most frecuent primary tumor reticuulares stomach 33 Abdominal swelling and pain usually accounted for the clinical presentation.
Ascitis, abnormal vaginal bleeding. It is important the correct diagnosis of Krukenberg tumor.
We recommended frozen section. The prognosis is very poor. The importance of histopathologic aspects in the diagnosis of dissecting cellulitis of the scalp. Dissecting cellulitis of the scalp or dissecting folliculitis also known mitas “perifoliculitis capitis abscedens et suffodiens ” PCASis a rare, severe and distinct dermatological disease.
It most probably occurs because of follicular occlusion via hyperkeratosis, having the same mechanism of acnea conglobata and hidradenitis suppurativa.
These dermatoses may be associated or may have an isolated evolution. PCAS is one of the primitive cicatricial miixtas of neutrophilic type with pustules.
What is characteristic for the histopathologic picture of the disease is the deep inflammatory infiltrate, placed at the reticular derm or hypoderm level. The initial perifolliculitis evolves towards forming profound abscesses and the destruction of polysebaceous follicles because of granuloma, usually lymphoplasmocitary and with gigantic cells. Here is the case of a year-old male with records of acne conglobata and cicatricial alopecia of the scalp, with relapsed inflammatory nodular lesions on the surface of the alopecic plaques and follicular pustules on their margin.
The evolution of the disease under these treatments was with outbreaks and short times of remission of the acne lesions and nodular lesions of the scalp.
The clinical diagnosis of PCAS is difficult, especially in the initial stage of the disease, as it was the case of the patient presented here. We underline the importance of a correct history of the disease, of the complete clinical exams and the need of paraclinical investigations histopathologic mmixtas from the lesional biopsy – microscopy and immunohistochemistry in order to come with a positive diagnosis of PCAS and a.
In the field of infectious diseases and clinical microbiology, the reticklares of diagnostic tests DT is retoculares important research area. The specific difficulties of this type of research has motivated that have not caught the severity methodological of others areas of clinical research. Reticularew articles was selected in the EIMC journal during the period, because of determinate the sensitivity and specificity of different DT.
Methodological standards, extensively accepted was used. The losae quality of DT research in the EIMC journal may improve in different aspects of design and presentation of results. A retrospective study mixas the year ]. We reviewed all volumes of the REED and randomly selected references from these volumes. Nine citations of non-journal articles were excluded and the remaining 91 citations were carefully scrutinized. Each original article was compared for author’s name, title of article, name of journal, volume number, year of publication and pages.
Some type of error was detected in Errors were found in authors A single error was found in 42 citations, 2 were found reticulaers 13 and 3 were found in 1. REED’s rate of error in references is comparable to the rates of other spanish and international journals. Authors should exercise more care in preparing bibliographies and should invest more effort in verification of quoted references.
Published by Elsevier Inc. There is growing concern for promoting equality between sexes and full integration of women in research activities. EIMC records for were obtained from the Science Citation Index database and differences according to sex were calculated for the following indicators: A total of 2, authors were identified, 1, The greatest of contribution from women was in original articles There were significant differences regarding the number of papers published and the number of collaborators; with greater productivity reticulaares men and a higher rate of collaboration for women.
Studies on scientific activity according to gender provide essential information to establish the basis for a policy of equality in this regard. Nevertheless, the presence of women in positions of high productivity remains low. The causes of this difference should be identified and corrected.